摘要
目的:回顾卡介苗(BCG)的应用情况,介绍关于结核疫苗研究进展的最新信息。方法:查阅大量关于结核疫苗研究的最近几年的文献。结果:有多种抗结核疫苗正在研究中,例如卡介苗、结核活疫苗、亚单位疫苗、DNA疫苗以及转基因植物疫苗等。结论:BCG仍是目前唯一可应用的抗结核疫苗,但是许多新疫苗己在动物模型中显示出潜力并开始进入临床试验。
Objective: To take a brief historic look at the use of current Bacille Calmette Guerin(BCG) vaccine and provide the up-to-date information on the latest developments in tuberculosis vaccine research. Methods: To collect and read lots of literature about antituberculosis vaccines, published in recent years. Results: There are many kinds of antituberculosis vaccines, such as the BCG vaccine, the live vaccine, the subunit vaccine; the DNA vaccine and the transgenic plants vaccine, and so on. Conclusion: BCG is still the only currently available vaccine, but many new vaccines for TB have shown promise in animal models and are just beginning to enter clinical trials.
出处
《大理学院学报（综合版）》
CAS
2005年第3期77-80,90,共5页
Journal of Dali University
关键词
结核杆菌
疫苗
基因组
预防
Mycobacterium tuberculosis
Vaccines
Genome
Prevention
