摘要
目的探讨癫痫儿童的认知功能状况,观察其事件相关电位的变化.方法选择临床确诊的8～14岁癫痫患儿和相应年龄组正常儿童各45人,组成实验组和对照组,利用瑞文标准推理测验,分别对两组儿童进行认知功能测试,并分别测定其事件相关电位.结果癫痫儿童有智能缺陷者达33.3%,其B、E分量表得分显著低于正常对照组(P<0.05);事件相关电位P300潜伏期较对照组显著延长(P<0.01).结论癫痫可导致儿童智力受损,以抽象概念形成能力和类比能力受损最为明显.事件相关电位P300潜伏期的变化是评价儿童智能状况很好的客观指标.
ObjectiveTo study the cognitive function and observe the changes of event-related potential of epileptic children.Methods45 epileptic children and 45 normal children were put in as the test group and the control group.The cognitive function and event-related potential were evaluated by means of Raven's standard Progressive Matrices (SPM) and evoked potential instrument respectively.ResultsAbout 33.3% epileptic children presented cognitive deficits.For children with cognitive deficits, their scores of B, E were significantly different from those in the control group(P<0.05).The latency of event-related potential P300 showed significantly prolonged than that of the control group (P<0.01).ConclusionEpilepsy may cause cognitive function deficit, especially in the ability of analog, analysis and abstract. The latency of event-related potential P300 is a very good objective to assess the cognitive function of children.
出处
《中国康复理论与实践》
CSCD
2005年第5期379-380,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
癫痫
认知功能
事件相关电位
P300
epilepsy
cognitive function
event-related potential
P300
