摘要
红毛五加醇提物和水提物有明显的中枢抑制作用,可以减少小鼠的自发活动,协同戊巴比妥钠的中枢抑制作用并拮抗苯丙胺的中枢兴奋作用。其中枢镇静作用似与安定有别,而相似与利血平。
xperimental data
indicated that Acanthopanax giraldii given intraperitoneally in nuce
had pronounced in-hibitory effects on the CNS. It reduced the
spontaneous activity , prolonged the hypnotic time of pentobarbital
sodi-um and antagonised the amphetamine-induced hyperactivity. The
results suggest that the sedative effect of A. gi-raldii is probably
different from that of diazepam , but perhaps similar to that of
reserpine.
出处
《中国中药杂志》
CAS
CSCD
北大核心
1994年第3期171-174,共4页
China Journal of Chinese Materia Medica
关键词
红毛五加
中枢神经系统
镇静
Acanthopanax gtdralii , central nervous system ,
sedation,acute toxicity