摘要
目的评价改良颅内外血管吻合术治疗缺血性脑血管病的疗效。方法对5例颈动脉闭塞患者行改良颅内外血管吻合术,分析术前、术后的脑血流动力学改变及临床症状,并进行7~12个月的随访。结果5例患者临床症状有所改善,在随访期间无卒中发生,单光子发射电子计算机断层扫描(SPECT)行局部脑血流量(rCBF)测定,显示脑血流量较术前有所增加。结论颅内外血管吻合术可有效地改善脑局部血流动力学状况及临床症状,预防完全性卒中的发生,远期疗效尚需进一步证实。
Objective To evaluate the effect of modified extracranial-intracranial bypass for the treatment of ischemic cerebrovascular disease. Methods 5 patients with occlusive carotid artery disease underwent modified EC/IC bypass surgery. Their hemodynamic and clinical data were analyzed before and after surgery. Results None of the five patients had stroke during the follow-up period. Clinical symptoms were improved. Regional cerebral blood flow (rCBF) measured by single photon emission computed tomography (SPECT) showed that rCBF was increased post operatively. Conclusion Extracranial- intracranial bypass surgery is effective to improve the rCBF and the clinical symptoms, and may prevent completely stroke. However the long term effect need to be further confirmed. SPECT is helpful to evaluate the effect of the surgery.
出处
《中国脑血管病杂志》
CAS
2005年第6期263-265,280,共4页
Chinese Journal of Cerebrovascular Diseases