摘要
以１０名慢性阻塞性肺疾病合并继发性肺动脉高压患者为对象，采用右心漂浮导管的实验方法，观察了１００ｇ白花前胡水煎剂对血流动力学、血气及其它指标的急性影响。结果表明，白花前胡能降低ＴＰＶＲ和ＰＡＭＰ，降低幅度与原ＴＰＶＲ、ＰａＣＯ２呈正相关。对ＣＯ及ＳＡＭＰ影响不大。未见降低ＰａＯ２、ＳａＯ２等副作用。
en patients with pulmonary hypertension
secondary to chronic obstructive pulmonary disease weregiven Baihuaqianhu,a traditional
chinese medicine,(the roots of peucedanum praerupturam Dunn),thechanges of central
hemodynamics and blood gas were studied.30min after the administration of themedicine ,total
pulmonary vascular resistance (TPVR) was reduced by 15%(from7.0 unit to 5.9
unit,P<0.05),pulmonary artery mean pressure(PAMP)reduced by 10%(from 4.OkPa to
3.6kPa,P<0.05),and lasted for 120 min;The decreased levels of TPVR correlated with those of
TPVR(r=0.639,P<0. 05)at rest.There was no significant difference between the values of cardiac
output(CO),totalsystemic vascularresistances(TSR)and PaO2,SaO2 before and after the
administration of the medicine。
出处
《中国医科大学学报》
CAS
CSCD
1994年第2期122-125,共4页
Journal of China Medical University
基金
国家"七.五"医学科技重点攻关课题
