摘要
目的探讨促肝细胞生长素(PHGF)联合前列腺素E1(PGE1)在慢性乙型重型肝炎中的疗效。方法60例慢性乙型重型肝炎患者随机分为治疗组30例和对照组30例,对照组采用常规治疗,治疗组在常规治疗的基础上加用PGE1、PHGF,治疗前后分别检测肝功能、PT。结果治疗30d后,治疗组显效率、死亡率、SB和PTA值分别为43.3%、36.7%、(120±102)μmol/L和(70±23)%,对照组分别为13.3%、63.3%、(202±87)μmol/L和(40±18%)。2组间显效率、死亡率、SB及PTA值差异存在显著性(P<0.01或0.05)。结论PGE1联合PHGF在治疗慢性乙型重型肝炎中有较好疗效。
Objective To explore the efficacy of PHGF combined with PGE_1 on chronic severe hepatitis B.Methods 60 cases with chronic severe hepatitis B were randomly divided into treatment group(30 cases) and control group (30 cases).Control group was taken regular regimen,while treatment group was given PHGF?PGE_1,in addition to regular regimen.Hepatic functions,PT were measured before and after treatment.Results After 30 days of treatment,in the treatment group,the significant erfficacy rates?the mortality and the value of SB,PTA were 43.3%,36.7%,(120±102)μmol/L,(70±23)%,respectively.These of control group were 13.3%,63.3%,(202±87)μmol/L,(40±18)%,respectively.There were significantly difference in the two groups(P<0.05 or <0.01).Conclusion The PHGF combined with PGE_1 was efficient to treat patients with chronic sever hepatitis B.
出处
《中国微生态学杂志》
CAS
CSCD
2005年第3期209-210,共2页
Chinese Journal of Microecology
