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硬膜外应用罗哌卡因与布比卡因在异体肾移植术中的比较研究

The comparision research of epidural Ropivocaine with Bupivocaine anaesthesia in renal transplantation
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摘要 目的:比较罗哌卡因与布比卡因在异体肾移植术中应用的麻醉效果及探讨其安全性。方法:5 0例行异体肾移植术患者,随机分为罗哌卡因(R)组与布比卡因(B)组进行硬膜外麻醉,每组各2 5例。记录两组患者麻醉诱导前、麻醉诱导后2 0min、手术开始后6 0min及术毕时的脉搏血氧饱和度(SpO2 )、平均动脉压(MAP)、心率(HR)和呼吸次数(RR) ,同时评价其麻醉效果和观察两组患者是否出现呻吟、肢体扭动、寒颤、皮肤过敏等并发症。结果:R组麻醉效果优良率为92 % ,B组为6 8% ,前者的优良率明显高于后者,P <0 .0 5。与B组比较,R组的RR ,SpO2 和MAP较为平稳,P <0 .0 5。结论:在异体肾移植术中,与布比卡因麻醉比较,罗哌卡因麻醉效果好且安全。 Object:To observe the efficacy and safety of of epidural Ropivocaine with Bupivocaine anesthesia in renal transplantation. Methods:50 patients, ASA 2~3 scores, undergoing renal transplantation were randomly divided into Ropivocaine (R)group and Bupivocaine (B)group, each group had 25 patients who accepted epidural anesthesia. SpO2、MAP、HR and RR were recorded at the time of pre-anesthesia,20 minutes post-induction, 60 minutes after operation and operation ending. Anesthesia efficacy and the side effects were observed peri -operation. Results:The efficacy in Group R was 92%, which was significantly higher than 68% in Group B, P<0.05. SpO2、MAP and RR in Group R had a minor change than those of Group B, P<0.05. Conclusions:Epidural Ropivocaine anesthesia worked well in renal transplantation and at the same time it was more efficient and safer than Bupivocaine.
作者 罗女 徐康清
出处 《赣南医学院学报》 2005年第2期193-194,共2页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
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  • 1Zaricd D, Axelsson K, Nydahl PA, et al. Sensory and motor blockade during epidural anesthesia with 1.0%,0.75% and 0.5% Ropivocaine: a double-blind study[J]. Anesth Analg, 1991,72:509-515. 被引量:1
  • 2徐仲煌,黄宇光,潘华,陈绍辉,任洪智,叶铁虎,罗爱伦.罗比卡因用于腰丛-坐骨神经联合阻滞的临床观察[J].临床麻醉学杂志,2002,18(5):235-238. 被引量:128
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