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乳腺导管内癌及伴微浸润的病理和临床特征 被引量:21

The clinical and pathological characteristics of breast ductal carcinoma in situ and with microinvasion
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摘要 目的 研究导管内癌(ductalcarcinomainsitu ,DCIS)及伴微浸润(DCISwithmicroinvasion ,DCIS MI)患者的病理与临床特征。方法 对1999年6月至2 0 0 3年6月收治的4 1例DCIS及Ⅰ、Ⅱ型DCIS MI患者的临床和病理学特点进行回顾性研究。结果 DCIS及Ⅰ、Ⅱ型DCIS MI的病理学特点不同;首发症状中,9 76 %的患者仅表现为乳腺摄影钙化灶(5 0 %为DCIS) ;乳腺摄影检查诊断符合率为80 % ,Ⅱ型DCIS MI乳腺摄影表现为肿块和腺体紊乱的比例为33 3% ,高于DCIS和Ⅰ型DCIS MI;5 7%的患者表现为乳头溢液,乳管内视镜诊断符合率为95 6 5 % ;局部复发2例,均为Ⅱ型DCIS MI患者。结论 DCIS与Ⅰ型、Ⅱ型DCIS MI病理和临床表现各有特点,因而预后也不同。 Objective To study the clinical and pathological characteristics of breast ductal carcinoma in situ (DCIS) and with microinvasion (DCIS-MI). Methods From June 1999 to June 2003, a total of 41 patients with DCIS and DCIS-MI patients were retrospectively studied. Results Pathology varies between DCIS type Ⅰ, type Ⅱ and DCIS-MI patients. Mammographic calcification was the only presenting symptom in 9.76% of patients with DCIS accounting for 50% of these cases. The accordance rate of mammography with final diagnosis was 80%, and 33.3% of mammography in DCIS-MI type 2 showed mass or chaos of gland construction. The initial symptom in 57% of patients was nipple discharge. For fiberoptic ductoscopy, the accordance rate was 95.65%. There were two local recurrent cases in DCIS-MI type 2. Conclusion Breast ductal carcinoma in situ and with microinvasion had their own characteristics, including different prognosis.
出处 《中华普通外科杂志》 CSCD 北大核心 2005年第4期235-237,共3页 Chinese Journal of General Surgery
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  • 1de Mascarel I, MacGrogan G, Mathoulin-Pelissier S, et al. Breast ductal carcinoma in situ with microinvasion: a definition supported by a long-term study of 1248 serially sectioned ductal carcinomas. Cancer,2002,94:2134-2142. 被引量:1
  • 2Silverstein MJ. Ductal carcinoma in situ of the breast: the treatment controversy. Breast, 2003,12(S1):8. 被引量:1
  • 3Fisher B, Dignam J, Wolmark N, et al. Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomized controlled trial. Lancet,1999,353:1993-2000. 被引量:1
  • 4Fisher ER, Dignam J, Tan-Chiu E, et al. Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of protocol B-17: intraductal carcinoma. Cancer, 1999,86:429-438. 被引量:1
  • 5Vicini FA, Recht A. Age at diagnosis and outconme for women with ductal carcinoma-in-situ of the breast: a critical review of the literature. J Clin Oncol, 2002,20:2736-2744. 被引量:1

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