摘要
目的 研究颈动脉颅外段斑块稳定性与青中年脑梗死。方法 对78例青中年脑梗死患者及6 9例对照组作颈动脉超声检查。结果 (1)青中年脑梗死组斑块检出率(5 3.9% )明显高于健康对照组(6 .6 % ) ,P<0 .0 5 ;(2 )青中年脑梗死组中不稳定斑块[软斑(37.7% )及溃疡斑(4.3% ) ]检出率高达4 2 % ,而稳定性斑块[扁平斑(4.3% )、硬斑(2 6 .1% ) ]检出率为30 .4 %。健康对照组仅2例发现斑块形成,两组比较差异有显著性(P<0 .0 5 ) ;(3)斑块好发于颈总动脉膨大处、颈内动脉起始处及颈总动脉主干;(4)青中年脑梗死组以轻、中度血管狭窄为主(7.8% ) ,老年脑梗死组以中、重度狭窄为主(36 .9% ) ,健康对照组无明显管腔狭窄。结论 青中年脑梗死患者颈动脉斑块具有不稳定性。斑块的组织学结构是影响其稳定性的内因,切应力作用是决定斑块稳定性的外因。在内因及外因的共同作用下,不稳定斑块成为青中年脑梗死的危险因素之一。
Objective To assess the stability of carotid plaque in young adult with acute cerebral infarction.Methods 78 young adult with cerebral infarction and 69 control subjects were examined with color duplx sonography.Results The incidence of the carotid plaque in young adult stroke patients was found to be 53.9%,while 6.6 % in control subjects.Cerebral infarction in young adult was correlated with the type of carotid plaque,especially soft plaque and ulcer plaque.There is a high prevalence of carotid plaque in CCA and ICA.The slight and moderate stenoses of the carotid arteries were found in young stroke patients,while the moderate and severe stenoses occurred in old patients.Conclusion The carotid plaque are instability which correlated with cerebral infarction in young patients.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2005年第2期163-165,共3页
Journal of Apoplexy and Nervous Diseases
