摘要
目的高选迷走神经切断贲门周围血管离断术对胃功能的保护作用。方法127例门脉高压病人随机分为两组,一组行高选迷走神经切断贲门周围血管离断术为研究组,另一组行常规贲门周围血管离断术为对照组。术后以血清胃泌素、胃酸的变化及胃蠕动的恢复情况为观察指标。结果血清胃泌素研究组为(88·70±13·07)pg/ml,对照组为(75·17±11·43)pg/ml,两组对比P=0·046。基础胃酸排出量研究组为(2·36±1·01)mEq/ml,对照组为(1·03±0·88)mEq/ml,两组对比P=0·033。最大胃酸排出量研究组为(5·87±1·83)mEq/ml,对照组为(3·89±1·02)mEq/ml,两组对比P=0·026。胃肠功能恢复研究组平均为2·9d,对照组平均组为5·2d,P=0·01。结论高选迷走神经切断贲门周围血管离断术既治疗了原发病,又保护了胃功能,减少了并发症,提高了病人的生活质量。
Objective To evaluate the protective effects of pericardial devascularization with highly selective vagotomy on gastric function. Methods A total of 127 patients were randomized into 2 groups. The patients in the experimental group were treated by pericardial devascularization with highly selective vagotomy and those in the control group by pericardial devascularization without highly selective vagotomy. Results The serum levels of gastrin, BAO and PMAO were 88.70±13.07 pg/ml, 2.36±1.01 mEq/ml and 5.87±1.83 mEq/ml and mean duration for recovery of gastroenteric peristalsis 2.9 d in the experimental group and 75.17±11.43 pg/ml, 1.03±0.88 mEq/ml, 3.89±1.02 mEq/ml and 5.2 d in the control, respectively (P=0.046, 0.033, 0.026 and 0.01). Conclusions The pericardial devascularization with highly selective vagotomy has lots of advantages in protecting gastric functions, reducing complications and improving patient's life qualities.
出处
《中华肝胆外科杂志》
CAS
CSCD
2005年第4期231-233,共3页
Chinese Journal of Hepatobiliary Surgery
