摘要
从我国湖北省武汉东湖土壤中分离到一株链霉菌,编号SIIA9268,其代谢产物具有免疫抑制作用,经鉴别活性物质与Rapamycin为同一物质。该菌株在形态培养特征和生理生化特征上与已知的吸水链霉菌相似,但又有一定的差别,故定名为吸水链霉菌东湖变种(Strepto-myceshygroscopicusdonghuensisSIIA9268)。
A strain SIIA9268 isolated from soil samples collected in
Wuhan,Hubei province of China has been found to produce immunosu-ppressant compound
and the properties of this active compound appears to be identical with Rapamycin. This
producing strain is similar to kno-wn Streptomyces hygroscopicus Rapamycin-produing
AYB-994 and Lono-mycin-producing strain SIPI-A4-0040,but still has some differences in
cultural and physiolgical characteristics.Therefore,it was named Strep-tomyces hygroscopicus
donghusis SIIA 9268.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1994年第6期412-414,共3页
Chinese Journal of Antibiotics
关键词
RAPAMYCIN
链霉菌
SIIA9268
鉴定
Rapamycin
Immunsuppressant
Streptomyces
hygrosc-opicus
Streptomyces hygroscopicus donghusis SIIA 9268