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脂联素及其分泌调节 被引量:21

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摘要 脂联素是脂肪细胞特异性细胞因子,其血浆水平与胰岛素抵抗、肥胖症、2型糖尿病以及动脉硬化疾病的发病有关。目前已克隆到脂联素受体,过氧化物酶增殖物激活型受体γ配体和肿瘤坏死因子等细胞因子以及β肾上腺素能受体激动剂等因素均可参与脂联素的表达和分泌。对脂联素的进一步研究可为代谢性疾病的防治提供一条新的思路。
出处 《中国动脉硬化杂志》 CAS CSCD 2005年第2期242-244,共3页 Chinese Journal of Arteriosclerosis
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  • 1Berg AH,Combs TP,Scherer PE.Acrp30/adiponectin:an adipocytokine regulating glucose and lipid metabolism.Trends Endocrinol Metabolism,2002,13(1):84-89. 被引量:1
  • 2Wang Y,Xu A,Knight C,Xu LY,Cooper GJ.Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin:potential role in the modulation of its insulin-sensitizing activity.J Biol Chem,2002,277(22):19 521-529. 被引量:1
  • 3Yoda-Murakami M,Taniguchi M,Takahashi K,Kawamata S,Saito K,Choi-Miura.Change in expression of GBP28/adiponectin in carbon tetrachloride-administrated mouse liver.Biochm Biophys Res,Commun,2001,285(2):372-377. 被引量:1
  • 4Pajvani UB,Hankins M,Combs TP,Rajala MW,Doebber T,Berger TP,et al.Complex distrbution,not absolute amount of adiponectin,correlates with thizolidinedione-mediated mprovement in insulin sensitivity.J Biol Chem,2004,279(13):12 152-162. 被引量:1
  • 5Pajvani UB,Du X,Combs TP,Berg AH,Rajala MW,Schulthess T,et al.Structure-Function Studies of the Adiponectin-Secreted Hormone Acrp30/Adiponectin.J Biol Chem,2003,278(11):9 073-085. 被引量:1
  • 6Tsao TS,Tomas E,Murrey HE,Hug C,Lee DH,Ruderman NB,et al.Role of Disulfide Bonds in Acrp30/Adiponectin Structure and Signaling Specificity.J Biol Chem,2003,278(50):50 810-817. 被引量:1
  • 7Yamauchi T,Kamon T,Minokoshi Y,Ito Y,Waki H,Uchidu S,et al.Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.Nature Medicine,2002,8(11):1 288-295. 被引量:1
  • 8Wu X,Motoshima H,Mahadev K,Stalker TJ,Scalia R,Goldstein BJ.Involvement of Amp-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes.Diabetes,2003,52(2):1 355-363. 被引量:1
  • 9Yamanchi T,Kamon J,Ito Y,Tsuchida A,Yokomizo T,Kita S,et al.Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.Nature,2003,423(6491):762-769. 被引量:1
  • 10Chinetti G,Zamadski C,Fruchart JC,Zawdski C,Fruchart JC,Steels B.Expression of adiponectin receptor in human macrophages andregulation by agonists of the nuclear receptor PPARalpha,PPARgamma,and LXR.Biochem Biophys Res Commun,2001,314(1):151-158. 被引量:1

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