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左氧氟沙星静点治疗老年人下呼吸道感染疗效观察 被引量:3

The Clinical Effectiveness of Levofloxacin Intravenously to the Old Patients with Lower Respiratory Infections
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摘要 目的:观察左氧氟沙星300mg qd和200mg bid静点治疗老年人下呼吸道感染的疗效。方法:使用左氧氟沙星 300mg qd和200mgbid静点,治疗中、重度下呼吸道感染62例。结果:前者与后者临床有效率分别为99%和90.6%,细菌 清除率分别为85%和87.5%,总有效率分别为90%和90.9%,痊愈率分别为66.7%和59.38%,不良反应率分别6.7% 和12.5%,经统计学处理,上述各项指标均无显著性差异(P>0.05)。结论:提示左氧氟沙星300mg静点qd的临床疗效 等同于左氧氟沙星200mg静点bid的临床疗效。 Objective: To investigate the clinical effectiveness of levefloxacin intravenously 300mg qd and 200mg bid in old patients with lower respiratory infections. Methods: Levofloxacin 300mg qd and 200mg bid were given intravenously to 62 patients with mild to severe lower respiratory infections.Results: To the levofloxacin 300mg qd and 200mg bid intravenously, the clinical effective rates were 99% vs 90.6% respectively; the bacteriological eradicative rates were 85% vs 87.5% respectively; the total effective rates were 90% vs 90.9% respectively, the cured rates were 66.7% vs 59.38% respectively; the side effect incidence rates were 6.7% vs 12.5% respectively. There was no statestic significance between the two strategies (P > 0.05). Conclusion: The clinical effectiveness was equally to the two strategies.
作者 陈娟 张健
出处 《中国医药导刊》 2005年第2期111-112,共2页 Chinese Journal of Medicinal Guide
关键词 左氧氟沙星 静脉点滴 治疗 老年人 下呼吸道感染 疗效观察 levofloxacin lower respiratory infections clinical trial old patients
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  • 1单爱莲,吕媛,李家泰.左旋氧氟沙星和氧氟沙星的临床应用进展与评价[J].中国临床药理学杂志,1997,13(2):115-119. 被引量:105
  • 2Martin SJ, Meyer JM, Chuck SK, et al. Lexofloxacin: new quinolone antibiotics [J ]. Ann Pharmaeother, 1998; 32 (3): 320 ~ 336. 被引量:1
  • 3Casellas JM, Gilardoni M,Tome G, et al. Comparative in - vitro activity of levofloxacin against is olates of bateria from adult patients with community - acquired lower respiratory tract infections[J] .J Antimicrob Chemother, 1999;43(Suppl C) :33 ~ 42. 被引量:1

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