摘要
用Fura—2/AM测定细胞内钙离子浓度,结果表明,5种海马提取物对L—谷氨酸致大鼠神经元钙内流有明显的抑制作用。其中大海马H.kuda的抑制作用最强,日本海马作用最弱,这与传统药材质量评价相一致。
Application of Fura - 2/AM measured the calcium concentration [Ca^(2+)] and the significant inhibitory effects of the extracts of 5 species of Hippocampus on exitatory amino acid L - glutamic acid induced Ca2+ influx in rats'neurons have been reported. The extracts from H. kuda showed the strongest effects and the extract from H. japonicus did weakly. This results are in line with traditional medical material quality evaluation.
出处
《中国海洋药物》
CAS
CSCD
1994年第4期6-9,共4页
Chinese Journal of Marine Drugs
基金
国家自然科学基金资助项目
