摘要
目的 研究鼻咽癌放疗后放射性脑病患者生存质量的变化及其与神经系统症状的相关性。方法 采用世界卫生组织生存质量量表简表(WHOQOL-BREF)、LENT/SOMA放射性损伤评估量表对病例组和对照组进行评定,并将文献提供的一般人群对照作为正常对照。结果 病例组在社会关系领域、总的健康和总的生活评分方面与对照组间差异有显著性意义(P<0.05)。病例组在生理、心理、社会关系、总的生活和总的健康评分与一般人群对照组间差异有显著性意义(P<0.05)。球麻痹症状与生存质量社会关系领域、总的生活健康评分呈负相关(P<0.05)。结论 除环境领域外, 放射性脑病对生命质量的其他方面存在一定的负性影响。球麻痹症状的存在对生存质量产生了较大的负性影响。
Objective Analyzing the change of quality of life of radiation encephalopathy after radiotherapy of nasopharyngeal cancer and the relationship with the nervous system symptoms.Methods The grades of headache and nervous system defect were evaluated by the WHOQOL-BREF and the LENT/SOMA scoring system. The assessments of the quality of life were done in order to analyze the correlation between the symptoms of RE and the quality of life. The common crowd offered by the reference was taken as the normal contrast. Results There is no significant difference in the social domain, health and life scoring from the normal contrast (P<0.05). There is the negative correlation among physiology, psychology, social relation, the whole life and the whole health scoring in the case group (P<0.05).Conclusion Beside the surrounding field, radiation encephalopathy has negative effect on some domains of the quality of life . The negative effect of bulbar palsy on the quality of life should be taken into account.
出处
《中国全科医学》
CAS
CSCD
2005年第7期561-562,共2页
Chinese General Practice
