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颈动脉粥样硬化的基因研究 被引量:4

Genetic Research in Carotid Atherosclerosis
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摘要 颈动脉内中膜厚度(IMT)是动脉粥样硬化亚临床的标志,与脑梗死的发病有关。研究发现,一些基因,如肝脂酶、载脂蛋白、胆固醇脂转移蛋白、对氧磷酶、血管紧张素转化酶、基质金属蛋白酶3、炎性细胞因子、内皮型一氧化氮合酶等变化时,IMT也可发生变化,从而增加卒中的风险。 Carotid intimal medial thickness (IMT) is a sign of subclinical atherosclerosis and is associated with the onset of cerebral infarction. Studies have found that IMT may also change when some genes change, such as hepatic lipase, apolipoprotein, cholesterester transfer protein, paraoxonase, angiotensin converting enzyme, matrix metalloproteinase 3, inflammatory cytokine (interleukin 6), and endothelial nitric oxide synthase, thus increases the risk of stroke.
作者 赵辉 丁素菊
出处 《国外医学(脑血管疾病分册)》 2005年第3期232-235,共4页 Foreign Medical Sciences Cerebrovascular Diseases
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