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脑缺血后炎症及其治疗对策 被引量:31

Inflammation After Cerebral Ischemia and Its Therapeutic Strategy
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摘要 越来越多的资料表明,炎症在缺血性脑损伤中起着重要作用。文章从基础研究和临床试验方面阐述了炎症细胞和细胞因子与脑缺血的关系,并探讨了影响炎症治疗的因素和应用前景。 Increasing data have shown that inflammation plays an important role in cerebral ischemic injury. The article presents the relationship between inflammatory cells or cytokines and cerebral ischemia from basic research and clinical trials, and also discusses the factors that affect the treatment of inflammation, as well as its application prospect.
出处 《国外医学(脑血管疾病分册)》 2005年第3期194-198,共5页 Foreign Medical Sciences Cerebrovascular Diseases
关键词 治疗对策 缺血后 缺血性脑损伤 细胞因子 炎症细胞 基础研究 炎症治疗 脑缺血 cerebral ischemia inflammation inflammatory cell cytokine
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参考文献31

  • 1Frijns CJ, Kappelle LJ. Inflammatory cell adhesion molecules in ischemic cerebrovascular disease. Stroke, 2002, 33: 2115 - 2122. 被引量:1
  • 2Jean WC, Spellman SR, Nussbaum ES, et al. Reperfusion injury after focal cerebral ischemia: the role of inflammation and the therapeutic horizon. Neurosurgery, 1998, 43:1382 -1396. 被引量:1
  • 3Matsuo Y, Onodera H, Shiga Y, et al. Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat. Effects of neutrophil depletion. Stroke, 1994, 25: 1469-1475. 被引量:1
  • 4Schaller B, Graf R. Cerebral ischemia and reperfusion: the pathophysi-ologic concept as a basis for clinical therapy. J Cereb Blood Flow Metab, 2004, 24:351 -371. 被引量:1
  • 5Clemens JA, Smalstig EB, Rash KS, et al. Global cerebral ischemia activates nuclear factor-κB prior to evidence of DNA fragmentation.Brain Res Mol Brain Res, 1997, 48:187 - 196. 被引量:1
  • 6Stephenson D, Yin T, Smalstig EB, et al. Transcription factor nuclear factor-κB is activated in neurons after focal cerebral ischemia. J Cereb Blood Flow Metab, 2000, 20:592 -603. 被引量:1
  • 7Yu Z, Zhou D, Bruce-Keller AJ, et al. Lack of the p50 subunit of κuclear factor-κB increases the vulnerability of hippocampal neurons to excitotoxic injury. J Neurosci, 1999, 19:8856 -8865. 被引量:1
  • 8Botchkina GI, Geimonen E, Bilof ML, et al. Loss of NF-κB activity during cerebral ischemia and TNF cytotoxicity. Mol Med, 1999, 5:372 -381. 被引量:1
  • 9Mattson MP, Culmsee C, Yu Z, et al. Roles of nuclear factor κB in neuronal survival and plasticity. J Neurochem, 2000, 74:443 -456. 被引量:1
  • 10Sharp FR, Lu A, Tang Y, et al. Multiple molecular penumbras after focal cerebral ischemia. J Cereb Blood Flow Metab, 2000, 20:1011 - 1032. 被引量:1

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