摘要
目的探讨癌胚抗原(CEA)和乳酸脱氢酶(LDH)及葡萄糖(Glu)水平在良恶性胸腹水中的临床鉴别诊断意义。方法分别采用化学发光标记免疫法、速率法和葡萄糖氧化酶法检测105例患者不同性质胸腹水中CEA和LDH及Glu的浓度,检测结果采用方差分析和Dunett’C法进行统计分析。结果恶性肿瘤组患者胸腹水标本中CEA值较结核性胸膜炎组和慢性非特异性炎症组明显升高(P<0.05);恶性肿瘤组和结核性胸膜炎组标本LDH值之间差异无显著性(P>0.05),但均高于慢性非特异性炎症组(P<0.05);恶性肿瘤组和慢性非特异性炎症组标本Glu值差异无显著性(P>0.05),但均高于结核性胸膜炎组(P<0.05)。结论联合定量检测CEA和LDH及Glu对胸腹水性质的鉴别诊断有重要临床参考价值。
Objective To explore the clinical differential diagnostic significance of carcinoembryonic antigen (CEA), lactate dehyrogenase (LDH) and glucose (Glu) in benign and malignant hydrothorax and hydroperiotoneum. Methods Chemilumiluminescent immunoassay (CLIA), velocity and glucose oxidase peroxidase (GOD-POD) method were used to determine the concentrations of CEA, LDH and Glu in the hydrothorax and hydroperiotoneum samples with different quality from 105 patients, respectively. The results were statistically analyzed by variance analysis and Dunett'C method. Results CEA values in the samples from patients with malignant tumor was remarkably increased compared with those of patients with tuberculous or chronic nonspecific inflammation(P<0.05). The LDH values in the samples from the malignant tumor patients and the tuberculous pleuritis did not show statistical difference(P>0.05), but higher than that from the chronic nonspecific inflammation(P<0.05). The Glu values in the samples from the malignant tumor patients and the chronic nonspecific inflammation patients were similar (P>0.05), but higher than that from the tuberculous pleuritis patients (P<0.05). Conclusion Quantitative co-detection of CEA, LDH and Glu can show important clinical reference value in differential diagnosis of hydrothorax and hydroperiotoneum quantity.
出处
《江西医学检验》
2005年第2期105-106,110,共3页
Jiangxi Journal of Medical Laboratory Sciences
基金
褚美芬
女
1965年生
大学本科
从事医学检验及相关研究。
