摘要
用自行设计的多级光学放大系统,观察到染色体上15nm大小的细微结构,用以研究致密状态的中期染色体超级结构,结合细胞化学技术,用特异性染色显示DNA-核蛋白、酸性骨架蛋白在染色体中的构象。本文发表了家猪染色体超级结构的天然形态──螺旋构型照片,描述了染色体螺旋结构的特征及其参数,提出了染色体超级结构的动态螺旋模型。
The super-structure of fine and close metaphase chromosomes was studied with the optical micro-multistage amplifying system designed by author himself, which could show the structure about 15nm in diameter of chromosomes. The micrographs of chromosomal super-structure made of DNA-nuclear protein or non histone protein wer shown respectively in the present paper. The chromotids were composed of long fibres about 20-30nm in diameter in a regular helical form directly.The Characters and paramerers of chromosomal super-structure were discribed, and a dynimical helical model of the chromosomal structure was suggested.This project supported by National Natural Sicience Foundation of China
基金
国家自然科学基金