摘要
采用显微分光光度法，对染色体脆性位点的部位进行了显微光谱学研究．实验证明，带有脆点的染色体其DNA含量大多数趋向减少，少数略有增加，推测染色体脆性部位的产生是由于染色质DNA在高度凝缩形成中期染色体过程中超螺旋结构改变的结果．
The position of fragilc sites in human chromosome was studied by means of the microspectroscopy. The results show that the amount of DNA in chromosome with fragile sites decreasesin most condition. We can suppose that the fragile sites of chromosome is caused by the superhelix structure changes of chromatin DNA during the formation of metaphase chromosome which is formed in high condensation.
出处
《遗传》
CAS
CSCD
北大核心
1994年第1期1-4,共4页
Hereditas（Beijing)
关键词
脆性位点
显微光谱学
人类
染色体
Human chromosomc, Fragile sites, Microspectroscopy
