摘要
目的评价氯诺昔康用于痔疮切除手术术后镇痛的效果和安全性。方法200例骶管麻醉下行混合痔外剥内扎手术,术后采用微量泵静脉自控镇痛(patientintravenouscontrolanalgesiaPICA)的病人,随机分为四组,Ⅰ组给予曲马多,Ⅱ组给予芬太尼,Ⅲ组给予氯诺昔康加芬太尼,IV组给予氯诺昔康。术后观察不同时点的疼痛发生率、程度(VAS评分)、副作用、术后生活质量和对疼痛处理的满意度等。结果Ⅱ组、Ⅲ组和IV组与Ⅰ组比较,术后VAS评分较低(P<0.05);与IV组比较,Ⅱ组、Ⅲ组镇痛的效果更好,但是Ⅲ组比Ⅱ组副作用更少,病人的术后生活质量和满意度更高(均P<0.05)。结论氯诺昔康用于痔疮切除手术术后镇痛是安全、有效的,能减少阿片类镇痛药的用量,副作用更少。
To access the analgesic effects and safeness of intravenous Lornoxicam on postoperative analgesia following hemorrhoids operations. Two hundred patients undergoing hemorrhoids operation,who received intravenous drug using continuous infusion pumps as postoperative analgesia,were randomized into four groups: group Ⅰreceived Tramadol, groupⅡreceived Fentanyl, group Ⅲ received Lornoxicam and Fentanyl, group IV received Lornoxicam. Postoperative pain was accessed with the incidence and the level (visual analogue scale, VAS); side-effect, quality of life after operation and satisfaction scale of dealing with pain was also accessed. Comparing with group Ⅰ, the group Ⅱ, group Ⅲ and group IV got decreased frequency and level of postoperative pain (P <0.05). Comparing with group IV, groupⅡand group Ⅲ has less incidence and level of postoperative pain, and group Ⅲ has less side-effect, higher life quality and higher satisfaction scale than group Ⅱ (all got P <0.05). [Conclusion] Intravenous Lornoxicam can effectively provide postoperative pain relief for after hemorrhoids operations with high effect and safeness, and reduce the dosage of Opium.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2005年第4期609-611,共3页
China Journal of Modern Medicine
关键词
氯诺昔康
痔疮切除手术
术后镇痛
lornoxicam
hemorrhoids operation
postoperative analgesia
