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重视对细菌产AmpC酶的检测与研究 被引量:1

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摘要 AmpC酶是革兰阴性细菌产生的头孢菌素酶,对β—内酰胺类抗生素严重耐药和对氨基糖苷类等多种抗生素交叉耐药,根据其产生机制分为染色体介导型和质粒介导型。检测方法主要为表型检测和采用PCR、核酸杂交技术等方法进行分子生物学检测。近年来AmpC酶的检出率逐年增高,细菌耐药性增强,应加强监测和研究。
出处 《世界感染杂志》 2005年第1期11-14,共4页 World Journal of Infection
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