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代谢综合征与血脂异常 被引量:16

Metabolic syndrome and abnormity of blood lipid
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摘要 代谢综合征是一个多症候群的综合征,其病因主要是胰岛素抵抗和肥胖。代谢综合征血脂异常主要表现为富含甘油三酯的脂蛋白升高、高密度脂蛋白胆固醇降低和小而密低密度脂蛋白增加。胰岛素抵抗及代偿性高胰岛素血症使极低密度脂蛋白合成增多,而脂蛋白脂酶活性下降导致空腹及餐后富含甘油三酯的脂蛋白清除下降和高密度脂蛋白胆固醇水平下降。脂蛋白异常显著增加了代谢综合征患者发生动脉粥样硬化性心血管病的危险性。对代谢综合征血脂异常的干预包括治疗性生活方式改变和药物治疗。
机构地区 中国医学科学院
出处 《国外医学(临床生物化学与检验学分册)》 2005年第2期77-79,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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