摘要
目的探讨多发性骨髓瘤(MM)患者骨损害程度与肝细胞生长因子(HGF)血清浓度的关系.方法采用双抗体夹心酶联免疫吸附法检测32例MM患者的HGF血清浓度,观察其与多发性骨髓瘤骨损害的关系.结果不同程度骨损害的MM患者,其血清HGF浓度的差异有统计学意义(P<0.01);MM骨损害越严重,其血清HGF浓度增高越显著.结论 MM患者HGF血清浓度与骨损害程度有关,骨损害程度严重者,HGF血清浓度明显增高.
Objective To explore the relationship between bone lesion and serum level of hepatocyte growth factor (HGF) in multiple myeloma (MM).Methods The serum levels of HGF were detected by enzyme-linked immunosorbent assay in 32 patients with MM, the correlation of HGF with bone lesion was evaluated. Results The serum levels of HGF among different grades of bone lesion in MM were significantly different (P< 0.01). The more severe the bone lesion in MM was, the more obviously the serum level of HGF elevated. Conclusion There was a positive association between serum level of HGF and bone lesion in multiple myeloma.
作者
陈盛亭
ZHANG Xue-li
张学利
曾慧兰
李娟
童秀珍
钟隽
张涛
CHEN Sheng-ting *,ZHANG Xue-li, ZENG Hui-lan, LI Juan,TONG Xiu-zhen, ZHONG Jun, ZHANG Tao *Department of Blood Transfusion, the First Affiliated Hospital of Jinan University, Guangzhou 510630, China
出处
《临床荟萃》
CAS
北大核心
2005年第6期305-306,共2页
Clinical Focus
基金
广东省医药卫生科研项目
