摘要
目的 探讨腹腔镜改良前列腺癌根治术 (LRP)治疗早期前列腺癌的疗效。 方法 2000年 10月至 2004年 9月,对 54例TNM分期为T1b^T2 的前列腺癌患者行经腹途径LRP。前期 15例(A组)按Monstouris法完成手术;后期 39例(B组)在熟悉LRP基本技术后进行技术改良:结扎耻骨后血管复合体,沿前列腺包膜锐性分离前列腺尖部,保留尿道括约肌和尿道直肠肌; 正确判断前列腺与膀胱颈交界部,保护膀胱颈环状肌环;横行离断膀胱颈后唇,在狄氏筋膜和膀胱肌外层之间向膀胱颈近端方向适当游离膀胱颈后唇;精细吻合后尿道与膀胱颈,将吻合口的前壁与耻骨后血管复合体固定。比较两组手术时间、出血量、围手术期并发症、术后控尿恢复时间和血清前列腺特异性抗原(PSA)值。 结果 54例手术均获成功。A、B两组平均手术时间分别为 390(270 ~660)min和 240(180~360)min; 平均出血量 430 ( 200 ~1100 )ml和 160 ( 100 ~400 )ml;手术并发症分别为 6例和5例;恢复控尿时间分别为 6个月和 3个月。以上指标两组比较差异均有统计学意义(P<0. 05)。血清前列腺特异性抗原(PSA)值A组 2例升高,B组随访 33例 1例升高 ( 6例近期完成手术者未复查),其余患者PSA均<0. 1ng/ml。 结论 随着手术技术的熟练和控尿技术的应用,LRP手术时间可缩短至 3h。
Objective To evaluate the therapeutic effects of functional reconstructive technique of laparoscopic radical prostatectomy (LRP) for organ confined prostate cancer. Methods From October 2000 to September 2004,54 patients with organ confined prostate cancer (TNM stage of T 1b-T 2) underwent LRP.After completion of the first group of 15 consecutive cases (group A) by Monstouris techniques, the functional reconstructive surgical technique, which is basically composed of anatomical radical prostatectomy,was introduced to LRP in the second group of 39 consecutive cases (group B).These techniques mainly consisted of preservation of urethral and bladder outlet sphincter muscles,reconstruction of bladder neck,and fine anastomosis between urethra and bladder neck with fixation of anterior wall of anastomotic stoma and retropubic vascular complex.The operative time, bleeding volume,complications,continence recovery time and PSA level were comparatively analyzed between the 2 groups. Results All the operations were successful in 54 patients.In group A and group B,the mean operative time was 390 min(range,270-660 min)vs 240 min(range,180-360 min);the mean bleeding volume was 430 ml(range,200-1100 ml) vs 160 ml(100-400 ml);the complication rate was 40% (6/15) vs 13% (5/39) and the continence recovery time was on average 6 months vs 3 months,respectively. There were statistically significant differences in these parameters between the 2 groups (P<0.05). Conclusions The functional reconstructive surgical techniques on the basis of perfect LRP can significantly reduce the complication rate, shorten the operative time and improve continence recovery.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2005年第3期176-179,共4页
Chinese Journal of Urology
