摘要
目的探讨高敏C反应蛋白(hs-CRP)是否是老年冠心病的危险因素,及与心血管事件发生率的关系。方法对233名老年冠心病患者,按照hs-CRP水平分成三组,随访18个月,观察心血管事件的发生率。hs-CRP<1.0mg/L为低危组,1.0-3.0mg/L为中危组,>3.0mg/L为高危组。结果各组发生心血管事件的比率分别为高危组36.4%,中危组21.1%,低危组14.8%;p=0.01。高危组的危险性是低危组的2.5倍。发生心血管事件者平均hs-CRP水平比未发生者高(2.77±2.16比1.78±1.76mg/L;p<0.05)。结论HS-CRP是老年冠心病的独立危险因素,并且能预示心血管事件的发生。
Objective To examine whether high-sensitivity C-reactive protein(hs-CRP)is a risk factor for coronary heart diseases in the elder, and the relationship between hs-CRP and cardiovascular events. Methods Hs-CRP were measured in 233 elderly patients with coronary heart diseases ,we assessed the risk of cardiovascular events associated with the levels of hs -CRP during a mean follow-up preriod of 18 months.The cutpoints of hs -CRP is low risk <1.0/L,average risk1.0 to 3.0mg/L,and high risk >3.0mg/L.Results The risk for future cardiovascular events in each tertile is :high-risk tertile 36.4%,average risk tertile 21.1%,low risk tertile 14.8%;p=0.01.The high-risk tertile has an 2.5-fold increase compared with the low-risk tertile. Hs-CRP are significantly higher in the patients with cardiovascular events than others(2.77±2.16 vs 1.78±1.76mgl/L;p<0.05).Conclusion Hs-CRP is an independent risk factor for coronary heart diseaes, hs-CRP maybe a predictor offuture cardiovascular events in elder.
出处
《中国病案》
2005年第3期44-45,共2页
Chinese Medical Record
