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多发性骨髓瘤的造血干细胞移植治疗现状及策略 被引量:2

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摘要 同传统化疗相比,大剂量化疗后的自体造血干细胞移植(AHSCT)能够使多发性骨髓瘤(MM)患者完全缓解(CR)率明显增加,生存率提高,逐渐成为目前65岁以下初治MM患者的标准一线治疗方法,但存在高复发风险。异基因干细胞移植(allo-SCT)具有潜在治愈MM的可能,但移植相关死亡率高,尚不能作为MM患者常规治疗手段,对于年轻的高危MM患者可以考虑。非清髓性移植在减轻预处理强度的同时保留了GVM(graft-versus-myeloma)效应,与自体干细胞移植联合应用有可能使MM患者预后得到进一步改善。
出处 《白血病.淋巴瘤》 CAS 2005年第1期61-64,共4页 Journal of Leukemia & Lymphoma
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