摘要
目的探讨大理州克山病病区及非病区人群发硒动态变化、相互关系及其差异的显著性.方法对大理州11个克山病病区县市366份发样、5个病区县的88份粮食样及1个非病区30份发样进行了硒含量测定分析,并对2个重病区人群发硒进行了11年的连续监测分析.结果克山病病区农业人口发硒水平在0.112～0.186 mg/kg,平均为0.154 mg/kg,粮食硒含量平均在0.016 mg/kg;病区非农业户的人群发硒含量达到0.208 mg/kg,而非病区发硒水平在0.267 mg/kg;病区农业人口的发硒水平与非农业人口发硒水平之间有统计学差异(P＜0.01),病区农业人口与非病区人群之间发硒水平也有统计学差异(P＜0.01).结论人群发硒水平也有逐年上升趋势,与克山病发病率逐年下降呈正相关关系.硒预防克山病效果显著.
Objective To explore dynamic change of hair selenium level in population, relationship and significant difference among Keshan disease areas and non-Keshan disease areas. Methods The content of selenium was detected and analyzed in 366 sets of hair in 11 Keshan disease counties, 88 sets of cereals in 5 Keshan disease counties and 30 sets of hair samples in 1 non-Keshan disease county. And hair selenium was surveyed in 2 Keshan disease areas with high incidence for 11 years. Results The level of hair selenium was from 0.112 to 0.186 mg/kg (the average was 0.154mg/kg) and the average of selenium in cereals was 0.016 mg/kg in farm population. The average of hair selenium in non-farm population was 0.208mg/kg and the average of hair selenium in non-Keshan disease areas was 0.267mg/kg. Hair selenium was significantly different between farm population and non-farm population(P<0.01). Meanwhile, there were significant differences in the level of hair selenium among farm population and non-farm population, Keshan disease population and non-Keshan disease population(P<0.01). Conclusions There was increasing trend of hair selenium level as positively correlated with the incidence decreasing of Keshan disease annually. Selenium application for prevention Keshan disease has significant effect.
出处
《地方病通报》
2005年第1期28-30,共3页
Endemic Diseases Bulletin
关键词
克山病
人群发硒
动态分析
Keshan disease areas
Hair selenium
Dynamic analysis
