摘要
将硫代对称二氨基脲(1)、3-烷基-4-氨基-5-巯基-1,2,4-均三唑(2)和双1,2,4-均三唑(5)在三氯氧磷存在下分别与香豆素-3-羧酸或苯并呋喃-2-甲酸等杂环羧酸缩合关环,得到了7种含香豆素和呋喃的均三唑并噻二唑多杂环化合物,产率为57%～70%.利用元素分析、MS、IR、1H NMR对化合物进行了表征.
Seven s-triazolo\-1,3,4-thiadiazole derivatives containing coumarin and furan were synthesized in yields of 57%～70% via the condensation of thiocarbohydrazide 1, 3-substituted-4-amino-5-mercapto-1,2, 4-triazoles 2 and 5 with various heterocyclic carboxylic acids in the presence of phosphorus oxychloride. The compounds obtained were characteriz ed by elemental analysis, IR, 1HNMR and MS.
出处
《应用化学》
CAS
CSCD
北大核心
2005年第3期316-319,共4页
Chinese Journal of Applied Chemistry
基金
泰山学院博士基金资助项目
