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前列地尔对减少糖尿病伴脑梗死患者24小时尿白蛋白排出量的临床观察 被引量:1

Clinical Observation of the Efficacy of Alprostadil in Reducing 24-hour-output of Urinary Albumin in Diabetic Patients with Cerebral Infarction
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摘要 目的 :观察前列地尔对糖尿病伴脑梗死患者24小时尿白蛋白排出量的影响。方法 :将56例糖尿病伴脑梗死患者随机分为治疗组 (30例 )和对照组 (26例 )。对照组给予复方丹参、生脉常规治疗 ,治疗组在对照组基础上加用前列地尔20μg,加入生理盐水100ml中静脉滴注 ,qd ,连用15d后进行疗效评定。结果 :治疗组临床疗效优于对照组 ,治疗组治疗后24小时尿白蛋白排出量与治疗前及对照组治疗后比较均有降低 (P<0 01、P<0 05)。结论 :前列地尔能有效地减少糖尿病伴脑梗死患者24小时尿白蛋白排出量。 OBJECTIVE:To observe the effect of Alprostadil in reducing24-hour-output of urinary albumin in diabetic patients with cerebral infarction.METHODS:56cases of diabetic patients with cerebral infaraction were randomly divided into treatment group(30cases)and control group(26cases);the control group were given the routine treatment,i.e.compound Danshen and Shengmai,for the treatment group,besides the routine treatment as stated in the control group,were given20μg Alprostadil that dispensed in100ml normal saline(NS)by intravenous drip,qd,for15days and then evaluated efˉfect.RESULTS:The therapeutic effect of the treatment group is better than that of the control group.Compared with that before treatment and that of the control group after treatment,the treatment group showed a lower level of24-hour-output of urinary albumin after treatment(P<0.01,P<0.05).CONCLUSION:Alprostadil can effectively reduce the24-hour uriˉnary albumin output in diabetic patients with cerebral infarction
出处 《中国药房》 CAS CSCD 北大核心 2005年第5期374-375,共2页 China Pharmacy
关键词 糖尿病 脑梗死 尿白蛋白 前列地尔 Diabetes Cerebral infarction Urinary albumin Alprostadil
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