摘要
从易得原料百菌清1出发,经过氟交换、氨解、水解、脱羧和酰化反应,合成得到10个新的多卤代苯甲酰基脲类几丁质抑制剂衍生物,总收率为30%～50%.所有化合物经HNMR,HREIMS,IR光谱证实.对化合物进行了生物活1性筛选,结果表明该类化合物对粘虫和蚊幼虫均有一定的杀虫活性.
Ten novel polyhalo benzoylphenylurea chitin inhibitor derivatives have been synthesized in over 30%similar to 50% yields from readily available starting material chlorothalonil 1 via fluorine exchange, aminolysis, decarboxylation and acylation reactions. All products were characterized by H-1 NMR, HREIMS and IR spectra. Preliminary bioactive research showed that some of the synthesized compounds have the potential insecticidal activities against Mythimna separata and Culex pipiens pallens.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2005年第3期304-307,共4页
Chinese Journal of Organic Chemistry
基金
云南自然科学基金(No.99B0005M)
南开大学元素有机化学国家重点实验室开放基金(No.200206)资助项目.
