摘要
【目的】探讨胎膜早破孕妇血清白细胞介素1β(interleukin 1β,IL 1β)水平与羊膜腔感染的关系。 【方法】用放射免疫法测定40例胎膜早破孕妇(早破组)和30例正常足月孕妇(对照组)血中IL 1β浓度,两组 孕妇均于产后留取胎膜送病理检查,确定有无绒毛膜羊膜炎。【结果】早破组血清IL 1β浓度为(0.3150± 0.09)μg/L,明显高于对照组(0.2020±0.07)μg/L,差异有显著性(t=5.72,P<0.01)。经病理证实的绒毛 膜羊膜炎组孕妇血中IL 1β为(0.3515±0.032)μg/L,非绒毛膜羊膜炎组为(0.2577±0.077)μg/L,两组差异 有显著性(t=4.60,P<0.01)。【结论】母血IL 1β水平可作为足月胎膜早破组织绒毛膜羊膜炎的一个预测 指标。
ObjectiveTo study the relationship between interleukin-1β(IL-1β)levels and the amniotic cavity infection in pregnant women with premature rupture of membranes (PROM)Maternal serum IL-1β level was measured by radioimmunoassay in 40 women with PROM and 30 normal full-term pregnant women. In the two groups ,the fetal postpartum membranes were kept for pathology examination to prove chorioamnionitis.The average IL-1β level was (0.3150±0.090)μg/L in the premature rupture of fetal membranes group ,significantly higher than that in the control(0.2020±0.070)μg/L,the difference was statistically significant (t=5.72,P<0.01).The IL-1β in the chorioamnionitis group was(0.3515±0.032)μg/L,and (0.2577±0.077)μg/L in the nonchorioamnionitis group, there was statistically significant difference between them (t=4.60 ,P<0.01).[conclusion]Maternal serum IL-1β is a pridictive marker for histological chorioamnionitis with PROM at term.
出处
《医学临床研究》
CAS
2005年第2期166-167,170,共3页
Journal of Clinical Research
关键词
胎膜早破
白细胞介素1/血液
fetal membranes,premature rupture
interleukin-1/BL
