摘要
本文探讨了脑梗塞急性期高血糖对患者近期预后的影响，６４例脑梗塞病人，根据血糖、果糖胺检测结果和既往糖尿病史分为三组：高血糖组、糖尿病组和血糖正常组。分别于入院时和第４周对患者的病情进行评分，以判断病情和预后，同时测定了患者的ＳＯＤ和ＬＰＯ。结果发现，血糖高的病人病情较血糖正常者重，预后差。同时其血中ＬＰＯ也升高，说明高血糖对脑梗塞患者的预后不利，自由基损伤是一个重要因素。
AbstractWe have prospectively observed the effects of hyperglycemia on prognosis of patients with acute cerebral infarction by means of quantitative methods.Blood superoxide dismuase(SOD)and lipid peroxide(LPO) were simultaneously measured.64 patients with acute cerebral infarction were divided into three groups:(1)Nondiabetic hyperglycemic group;(2)diabetic group;(3)nondiabetic normoglycernic group.Neurological impairments were quantified.The results showed that nondiabetic hyperglycemic group had the worst outcomes and the most severe neurological impairments,while diabetic group had moderate and nondiabetic normoglycemic group had the least neurological impairments. In all three groups,nondiabetic hyperglycemic group had the highest blood LPO levels nondiabetic normoglycemic grotip had the lowest,It is suggested that hyperglycemia would worsen the prognosis of cerebral infarction patients,in which LPO may, play an importment role.
出处
《临床神经病学杂志》
CAS
1994年第5期265-267,共3页
Journal of Clinical Neurology
