摘要
我们应用ｐ５Ｇ１γ－晶体蛋白基因探针，对Ｃｏｐｐｏｃｋ白内障家系成员的γ－晶体蛋白基因区存在的多态性进行了检测，发现了５个单体型，通过限制性片段长度多态（ＲＦＬＰ）连锁分析，未发现γ－晶体蛋白基因簇与白内障的位点有连锁关系。
Polymorphisms and haplotypes identified by DNA restriction fragment length polymorphisms in the gamma-crystallin gene region were investigated in the members of a family with Coppock cataract, using genomic DNA hybridization analysis with p5G1 probe encoding gamma-crystallin.Six of eight possible haplotypes were found in the members of the family. We did not find the linkage between the gamma-crystallin gene cluster and the locus for the Coppock cataract.
出处
《哈尔滨医科大学学报》
CAS
1994年第5期379-381,共3页
Journal of Harbin Medical University
基金
省自然科学基金
