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成熟颈上神经节移植于成年大鼠脊髓内存活的实验研究

VIABILITY OF MATURE SUPERIOR CERVICAL GANGLIA TRANSPLANTED IN THE SPINAL CORD OF ADULT RATS
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摘要 本文将成熟的颈上神经节(SCG)同种异体移植到成年大鼠脊髓腰膨大(Th_(13)或L_1)。对移植的节后交感神经元形态变化和存活生长进行了组织学和荧光组织化学的观察。实验结果表明:虽然移植神经细胞的大小和荧光强度仅部分达到正常,但仍证实移植的节后交感神经元在脊髓实质中能生存达3个月之久,并继续保持产生去甲肾上腺素的能力,从而呈现儿茶酚胺特殊荧光。根据实验资料,讨论了哺乳类脊髓移植和颈上神经节作为移植物的一些特点。 The morphological change and viability of mature rat superior cervical ganglia (SCG) were studied using histology and fluorescence histochemistry technique follo- wing homologous transplantation to adult lumbar spinal cord (Th13 or L1). It was shown that implanted postganglionic sympathetic neurons could survive for up to 90 days and continued to produce noradrenaline, which is responsible for the catecholamine specific fluorescence, although only a part of the surviving ganglionic neurons appeared normal in size, shape and intensity of the fluorescence. The characteristic features of the transplantation in mammalian spinal cord and the SCG as the implant tissue were discussed according to the experimental data.
出处 《神经解剖学杂志》 CAS CSCD 北大核心 1989年第1期83-87,共5页 Chinese Journal of Neuroanatomy
关键词 颈上神经节 神经移植 脊髓 superior cervical ganglion, transplantation, lumbar spinal cord, noradrenaline, fluorescence histochemistry
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