摘要
本文介绍了人精子在体外经二硫化碳染毒后，与去透明带金黄地鼠卵受精，体外培养，然后制备人精子染色体进行核型分析，结果表明染毒组（２５０ｍｇ／Ｌ）染色体断裂均数为０．１４００，与阴性对照组（０．０５３０）比较虽有升高，但无显著性差异（Ｐ＜Ｏ．０５）。
Carbon disulfide(CD)are the compound which could be frequently exposed toworkers in chemical industrial process. To evaluate the potential genetic risks of thecompound,163 karyotypes of human sperm chromosomes were analyzed,using Zona-freehamster eggs penetrated in Vitro by human spermatozoa after being treated the dosage(250mg/L)of CD. The result showed that the breakage mean in the group exposed to CDwas 0.1400,in the control was 0.0530,the difference between two groups was notsignificant(P>0.05).
出处
《癌变．畸变．突变》
CAS
CSCD
1994年第5期12-13,共2页
Carcinogenesis,Teratogenesis & Mutagenesis
关键词
二硫化碳
人
精子
染色体畸变
职业危害
carbon disulfide
human spermatozoa
chromosome aberration
