摘要
本文采用姐妹染色单体交换(SCH)方法,作吸烟者的体内研究和香烟冷凝物(CSC)的体外研究。结果表明,CSC可引起人外周淋巴细胞姐妹染色单体交换率(SCE_(?))的增加,有剂量反应关系。吸烟者与非吸烟者比较表明,吸烟者的SCE_(?)比非吸烟者高,但未见剂量反应关系。
Genetic toxicological methods, showed that cigarettes smoke condonsates induce sister ohromatid exchange in human peripheral blood lymphocytes. The frequancy of these changes show a dose-response relationship,smokers showed higher frequencies then non-smokers, but there was no dose-response relationship.
出处
《上海医科大学学报》
CSCD
1989年第6期446-448,共3页
Journal of Fudan University(Medical Science)
关键词
香烟冷凝物
姐妹染色体
SCE
cigarette smoke condensate
sister chromatid exchange