摘要
本文报告了抗人和不同种属哺乳动物(小鼠、牛、猪)输卵管多克隆抗体的初步鉴定及种属交叉反应性的研究结果。结果表明:(1)不同种属动物输卵管中存在着较多的共同抗原或共同抗原决定簇;(2)抗猪和牛输卵管抗体与人输卵管抗原有明显的交叉反应性。提示人和猪以及人和牛输卵管抗原中存在较多类似的抗原决定簇。鉴于透明带抗原有卵巢源和输卵管源,因此本研究结果为人和猪透明带抗原中存在着明显交叉性提拱了部分依据。
The present paper reported the results of preliminary identification and cross-reactivity of the antibodies against oviduct antigens from different mammalian animals and human.The SDS- PAGE and two dimensional polyacrylamide gel electrophoresis in conjunction with the immunoblotting assay were used.Our preliminary results come to the conclusions that:(1)there were more common antigens or epitopes of common antigens in oviducts of different mammalian animals;(2)the antibodies against porcine and bovine oviduct antigens could cross-react more strongly with human oviduct anti- gens,It is suggested that there are more common epitopes of oviduct antigens between human and por- eine oviducts,and between human and bovine oviducts.The result seems to be consistent with predomi- nant cross-reactivity existed in antigens of zonae pellucidae of pig and human.
出处
《生殖医学杂志》
CAS
1993年第2期99-101,共3页
Journal of Reproductive Medicine
关键词
输卵管
抗原
抗体
交叉反应
Oviduct
Antigens
Antibodies
Cross reactions
