摘要
用微量凝集与制动试验测定了229对原因不明不育症夫妇、151对已查明不育原因的不育夫妇和30对有正常生育力夫妇血清中抗精子抗体(ASA)。结果显示,两组不育患者血清ASA阳性率分别为12.2%和9.9％,均高于正常对照组。无论男方或女方,两组间的阳性率比较均无差异。但组内女方阳性率均高于男方。提示在部分已查明不育原因的患者中合并存在抗精子免疫性不育。
Serum antisperm antibodus in 229 couples wiiii un.xplain .d infirtilii'y (Group A) and 151 infertile couples with determined causes (Group B) were, assayed by a micro-agglutinatioa and iamobilization test.Infertility causes in Group B included sndometriosis, ovarian disfunction ,oviduct or csrvix disorders, oligozoosperrnia and asthenozoospermia. Thirty |criile control couples were also studied.Samples from 56 patients in Group A (12.2%; and 30 in Group B(9.9%)were positive for ASA, significantly different from fertile controls (P<0.01 and<0.05, respectively) . In detail, sera from 9.2% of males and 15.3% of females in Group A and 4.6% of males and 15.2% of females in Group B were positive. In both groups, ASA occurrence in female is more frequen i: than in male(P<^0.05). Results suggest that the immunological factor coexists with other infertility factors in some socalled 'determined causes' infertile patients, especially in wom-ii
出处
《重庆医科大学学报》
CAS
CSCD
1993年第3期199-201,共3页
Journal of Chongqing Medical University
