摘要
对京津地区5个医院590名护士的715次妊娠进行了分析,其中抗癌药接触组377次妊娠,对照组338次妊娠。结果表明,抗癌药接触组护士足月产率明显低于对照组(79.8%,89.6%),而早产率(5.3%.2.4%)、自然流产率(13.3%,7.7%)以及子代出生缺陷率(31.0‰,9.7‰)明显高于对照组。表明护士职业接触抗癌药对胚胎及胎儿发育有不良影响,应加强防护措施。
The study was carried out in five hospitals in Beijing and Tianjin.590 nurses were involved,715 pregnancies weredescribed in which 377 were exposed to antineoplastic drugs and 338 were unexposed.The results showed that the frequency offull—term birth was significantly lower in the exposed nurses than that in the unexposed nurses(79.8% vs 89.6%);the ??incidences of premature birth(5.3%,2.4%)and spontaneous abortion(13.5%,7.7%)and congenital malformations(31.0‰,9.7‰)in the offsprings of the exposed nurses were significantly higher than those of the unexposed nurses.Theresults indicated that occupational exposure to antineoplastic drugs during pregnancy may cause adverse effects on embryos andfetal development.Protective intervention methods shuld be used by all persons handling antineoplastic agents.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
1993年第3期139-142,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
抗癌药
先天畸形
护理人员
Nurse
Antineoplastic drug
Congenital malformation
Spontaneous abortion
