摘要
胃腺类癌是较少见的一种不典型性胃类癌。组织学上以内分泌型癌细胞呈腺体排列为特征。本文在透射电镜下观察了胃腺类癌的超微结构,看到胃粘膜中内分泌型癌细胞呈腺体排列,细胞浆内有特征性的内分泌颗粒,其中有一例伴不完全型肠型化生。癌组织中混杂少量粘液型细胞,个别癌细胞浆内有内、外分泌型二种颗粒。超微结构特征提示胃内、外分泌型癌细胞可能同源于内胚层的多潜能干细胞。
The ultrastructural features of gastric adenocarcinoids which are considered to be extremely rare were studied. Two gastric adenocarcinoids showed the histological characteristics of glandular arrangement, mainly containing endocrine cells. In the endocrine cells, specific endocrine granules can be divided four kinds, and incom- plete type intestinal metaplasia occurred. We are unaware of any reports of gastric adenocarcinoids together with intestinal metaplasia and hereby report a unique instance. In many areas the carcinoidal pattern merged with mucin-producing cells, and the individual cells contained both endocrine granules and mucinous droplets. These ultrastructural findings support the view that gastric adenocarcinoid cells originate from the totipotent stem cells of endodermal origin.
出处
《上海第二医科大学学报》
CSCD
1989年第4期294-298,共5页
Acta Universitatis Medicinalis Secondae Shanghai
关键词
超微结构
胃类癌
肠化
胃肿瘤
ultrastructure gastric carcinoid intestinal metaplasia
