摘要
46例确诊为急性心肌梗塞(AMI)的患者,随机分为镁(Mg^(2+))治疗组(n=23)和对照组(n=23)。治疗组入院后加用2.08mmol/L(25％)硫酸镁30ml和0.56mmol/L(10％)葡萄糖500ml缓慢静滴,维持24h。以带有微机存贮心电信号的监护仪进行监护,给药前后测定血清Mg^(2+)及其它电解质含量。结果:治疗组严重室性心律失常的发生率显著低于对照组(P<0.05);治疗过程中未引起患者血压明显波动及ECG间期异常,也未见其它副作用;治疗前后血清Mg^(2+)及其它电解质平均含量均在正常范围。
46 patients with acute myocardial infarction (AMI) were randomly assigned to the magnesium treated group (n=23)and the control group (n=23). The magnesium-treated group received 30ml of 25% magnesium sulfate in 500ml of 10% glucose during a period of 24 hours intravenously. All patients were subject to 24-hour bedside and central console ECG monitoring (Siemens, Sirecust 960, 120c). Blood samples for determination of serum Mg^(2+), K^+, Na^+and Ca^(2+)levels were taken before and after medication. The result showec that the incidence of threatening ventricular arrythmia in magnesium- treated group was much lower than that in the control group (P<0.05). Magnesium infusion did not affect blood pressure, PR interval, QRS complex and QT interval. Serum Mg^(2+) and other electrolytes (K^+, Na^+, Ca^(2+) levels were within the normal range in all pa- tients before and after the infusion of magnesium.
出处
《中国危重病急救医学》
CAS
CSCD
1993年第5期274-276,共3页
Chinese Critical Care Medicine
关键词
心肌梗塞
硫酸镁
心律失常
myocardial infarction
magnesium sulfate
arrythmia
