摘要
本文分析了946例孕妇乙肝病毒血症与围产儿的关系,结果发现:①妊娠合并乙肝组其早产率为16.10％,是正常孕妇的3.87倍,围产儿病死率为39.68‰,是正常组的4.99倍;②妊娠合并乙肝组新生儿窒息率达9.92％,为单纯妊娠期肝损的3.67倍;③有无乙肝病毒感染对胎儿宫内生长发育无明显影响,但有无肝功能损害对胎儿生长有一定影响;④有乙肝病毒感染组其妊高征发生率、产后出血率均明显高于正常组,⑤HBsAg和HBeAg均阳性者其母婴传播率为83.23％,新生儿肝炎发病率为16.67％,对母血乙肝病毒血症阳性的新生儿予乙肝疫苗预防接种,随访6至12个月婴儿出现免疫抗体阳性率为70％。
This paper analysed the relation between hepatitis-B viremia and the perinatals in 946 pregnant women. The results showed: (1)The incidence of premature labor in the HBV infected group was 16.10%, being 3.87 times that of the normal group. The perinatal mortality was 39.7%, which was 4.99 times of the normal group; (2)The incidence of neonatal asphyxia in HBV infected group was 9.92%, which was 3.67 times of those with only elevated liver enzymes; (3)There was no obvious influence on fetal development whether the pregnant women had HBV infection or not. however,abnormal liver function can influence the intra--uterine fetal growth; (4)There was higher incidence of EPH--syndrome and postpartum hemorrhage in the HBV infected group than in the normal group; (5)The maternal--fetal transmission rate of HBV was 83.3%, and in the patients whose HBsAg and HBeAg were all positive, the incidence of neonatal hepatitis--B was 16.67% in neonates born to sero-HBV positive mothers. 70% neonates developed antibody 6--12 months after immunization.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
1993年第5期279-280,共2页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
围产儿
乙型肝炎
母婴传播
Perinatal Hepatitis—B
Maternal fetal transmission of HBV
