摘要
检测了２２０例糖尿病患者的桡骨骨密度（ＢＭＤ）、血钙（Ｃａ）、磷（Ｐ）、硷性磷酸酶（ＡＬＰ）、空腹血糖（ＦＢＧ）、Ｃ肽、甲状旁腺激素（ＰＴＨ）、降钙素（ＣＴ）、２４小时尿Ｃａ和羟脯氨酸（ＨＯＰ）。结果显示骨量减少有９４例，为４２．７％，其中ＢＭＤ－１ＳＤ４４例，占２０％，－２ＳＤ５０例，占２２．７％。ＢＭＤ减少组２４小时尿Ｃａ、ＨＯＰ、ＡＬＰ明显高于骨量正常组（Ｐ＜０．０１）；年龄、病程、血糖控制水平及伴糖尿病肾病是ＢＭＤ变化的主要影响因素。在ＮＩＤＤＭ组中，ＢＭＤ与Ｃ肽／ＦＢＧ的比值呈正相关（ｒ＝０．５４６，Ｐ＜０．０１）。
in this study, 220 diabetic patients received determination of bone mineral density (BMD)of radius, serum calcium (Ca), phosphorus (P), alkaline phosphatase (ALP), fasting blood glucose ( PBG),C-peptide, parathormone (PTH),calcitonin (CT), 24h urine calcium (24h U-Ca) and hydro xy proline (Hyp). The results indicated that 94 cases (42. 7%) developed osteopenia, of whom 44 cases (20%) had BMD lying within X-1 SD and 50 cases (22. 7%) had BMD slying within X-2 SD. The 24h U-Ca,Hyp and ALP in the groups with lower BMD were obviously higher than those in the groups with normal BMD ( P <0. 01 ). The age ,duration of diabetes,level of blood glucose and complication of diabetic nephropathy were main affecting factors in the changes of BMD. A positive correlation (r=0. 546,P <0. 01 ) between BMD and the ratio of C-peptide to FBG was observed in the non-insulin-dependent group.
出处
《中国骨质疏松杂志》
CAS
CSCD
1996年第1期6-8,34,共4页
Chinese Journal of Osteoporosis
