摘要
目的通过检测乳腺癌患者血浆GST－π水平，阐明其在乳腺癌患者的临床意义。方法用放射免疫分析方法（Ridoim－munoassay，RIA）检测了乳腺癌、乳腺良性肿瘤患者及健康女性血浆中GST－π含量及乳腺癌患者手术前后血浆GST－π水平的变化。结果乳腺癌患者血浆GST－π水平为（931±4．48）μg／L、，阳性率64．7％，乳腺良性疾病患者血浆GST－π水平为（675±235）μg／L，阳性单6．9％（P＜0．05）。且乳腺癌患者手术前后水平差异明显。结论研究结果表明．检测患者血浆GST－π水平有助于乳腺癌的诊断及判断手术治疗效果。
Purpose To investigate the clinical significan of GST-π in patients of breast neoplasma. Methods By the meth-ods of radioimmunoassay (RIA) the level of GST-π in plasma in subjects breast carcinoma, benign breast tumor andhealthy control were measured, the relationship between the GST-π level and the clinical features of patients was alsostudied. Results The results demonstrated the difference of GST-π 1evel between malignant and benign breast tumorsis significant(positive rate of the former is 64. 7 %,the later is 6. 9 %,P<0. 05 ). The GST-π level of post-operation ismarkably reduced. Conclution The results showed that GST-π in plasma is helpful for diagnosing breast cancer andcan be used for judging the effectiveness of operation.
出处
《华北煤炭医学院学报》
1999年第6期497-498,共2页
Journal of North China Coal Medical College
