摘要
本文以棉产区和稻产区足月新生儿为研究对象,比较了两地区新生儿脐带血胆碱酯酶活性,并以研究对象家中农药使用情况为环境暴露指标,以新生儿脐带血胆碱酯酶活性为效应指标,分析了两者间的关系。逐步回归结果说明在棉产区使用呋喃丹、敌敌畏与脐带血胆碱酯酶总活性呈负相关关系。经统计学检验两地区脐带血胆碱酯酶活性及农民和非农民新生儿脐带血胆碱酯酶活性均未见显著性差异。本文还提供了农村地区脐带血胆碱酯酶活性的平均水平。
In this article the newborns of term deliv- ery were the subjects. The activity of choline- sterase of umbilical blood of newborns in cot- ton growing area were compared with those in rice growing area and were also compared bet- ween the farmers and nonfarmers in the two areas. The application of pesticides in the fam- ily of the subjects was used as index of expo- sure and the activity of cholinesterase of new- born's umbilical blood was used as index of effect. The relationship between the two indices were analyzed. The results demonstrated that there didn't exist significant difference of the activity of cholinesterase of umbilical blood bet- ween two areas and farmers and nonfarmers. The activity of cholinesterase was used as ind- ependent variable and the 15 kinds of pesticides were used as independent variables. Their rela- tionship was analyzed by stepwise regression analysis. The results demonstrated that there existed the negative correlation between the application of carbofuran and dichlorvos and total cholinesterase activity. This article still provided the average activity of cholinesterase of umbilical blood of newborns in rural areas.
关键词
农药中毒
新生儿
脐带血
胆碱酯酶
Newborn's umbilical blood Cholinesterase activity Environmental exposure to pesticides
