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来氟米特的合成 被引量:2

How to synthetize lefunomide
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出处 《河北职工医学院学报》 2001年第4期6-7,共2页 Journal of Hebei Medical College for Continuing Education
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  • 1Bertolini G,Aquino M,Biffi M,et al. Leflunomide,an immunorestoring drug for the therapy of autoinnune disorders, especially rheumatoid arthritis [ J ]. Transplant Proc,1996,28: 3074 - 3078. 被引量:1
  • 2Giorgio B, Mario A, Mauro B, et al. A new rational hypothsis for the phamacophore of the active metabolite of leflunomide, a potent immunosuppressive drug [ J ]. J Med Chem, 1997,40(13) :2011 - 2016. 被引量:1
  • 3Hiroyuki yasuda. Syntheses of 4,5 - disubstitutedisoxazoles and their cleavage reaction with sodium ethoxide. Yakugaku Zasshi 1959,79(6) :836 - 838. 被引量:1
  • 4Kaemmerer FJ, Schleyerbach R. Isixazike derivative [P].DE: 2854439,1980 - 07 - 03. (CA. 1980,93: 239392m). 被引量:1
  • 5Karolyl,GaborD,Jozsef F. GB. 2135996(1984). 被引量:1
  • 6Doleshall G, Seres, P, Isoxazole - oxazole conversion by Beckmann rearrangement [J ]J Chem Soc Perkin TransI,1988, (7): 1875 - 1879. 被引量:1
  • 7Fossa P, Menozzi G. 5 - Substiuted 4 - isoxazoleearboxarnides with platelet antiaggragating and other activties. Farmaco, 1991,46: 789 - 802. 被引量:1

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