摘要
目的：探讨免疫因素在脑性瘫痪发生、发展中的作用机制。方法：采用双抗体夹心ＥＬＩＳＡ法和Ｈ３＿Ｔｄｒ渗入法分别检测脑瘫患儿血浆白细胞介素６（ＩＬ＿６）、肿瘤坏死因子α（ＴＮＦ＿α）、ｌｇＧ、ｌｇＭ、ｌｇＡ含量及淋巴细胞转化率。结果：脑瘫患儿血浆ＩＬ＿６、ＴＮＦ＿α、ＩｇＧ、ＩｇＭ含量明显高于正常对照组。（Ｐ＜０．０１）。淋巴细胞转化率低于正常对照组。中、重度及极重度运动障碍组血浆ＩＬ＿６、ＴＮＦ＿α亦明显高于轻度组（Ｐ＜０．０１）。结论：免疫因素在脑瘫的发病机制中起重要作用。在开展现代康复的基础上，改善免疫功能十分重要。
Objective:to explore the mechanism of immune factors in the development of cerebral paralysis.Methods:ELISA and H 3 _Tdr were used in measuring the contents of IL_6,TNF_ ,IgG,IgM and the rate of lymphoid cell transfer in serum of children with cerebral paralysis .Results:The contents of IL_6,TNF_,IgG,IgM in serum of children with cerebral paralysis were obviously higher than the normal group (P<0.05),the rate of lymphoid cell transfer was lower than the normal group.The contents of IL_6,TNF_,in serum of medium and severe group were also much higher than the mild group.Conclusion:Immune factors play an important role in the pathogenic reasons of cerebral paralysis,so it is very important to improve immune function of the children on the basis of rehabilitation.
出处
《现代康复》
CAS
CSCD
1999年第7期804-805,共2页
Modern Rehabilitation
