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人低分化鼻咽癌上皮细胞系单克隆株的建立及其生长特性分析 被引量:2

THE CYTOELECTROPHORESTIC ANALYSIS FOR THE LOW DIFFERENTIATED NASOPHARYNGEAL CARCINOMA CELL STRAIN (CNE-2Z) AND ITS 21 SUBCLONES
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摘要 利用细胞电泳技术对低分化鼻咽癌细胞系(CNE-2Z)及其21个单克隆细胞株进行检测。CNE-2Z系平均细胞电泳率为1.43±0.35,21个单克隆平均细胞电泳率高低不一,从0.87±0.15到1.72±0.15,说明作为群体细胞系的CNE-2Z在细胞电泳方面具有明显异质性.同时,检测结果初步提供了21个单克隆株的纯度和转移能力的线索. The low differentiated nasopharyngeal carcinoma cell strain and its 21 subclones were tested with the cytoelectrophorestic technique. The electrophorestic mobility of CNE- 2Z was average 1. 43±0. 35,while that of 21 subclones varied each other,from average 0. 87±0.15 to 1.72±0.15 . The results indicated that,to be a population cell strain,CNE-2Z had an obvious heterogenicity in cytoelectrophoresis. Meanwhile, the results suggested that there be a preliminary data of the quality and the metastatic ability in 21 subclonal cell lines.
出处 《湛江医学院学报》 1993年第1期20-22,共3页
关键词 鼻咽肿瘤 细胞培养 单克隆 电泳 rhinopharyngeal carcinoma cell culture subclone electrophoresis
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  • 2谷淑燕,赵文平,曾毅,唐慰平,赵明伦,邓惠华,李昆.从低分化鼻咽癌病人建立鼻咽癌上皮细胞株[J]癌症,1983(02). 被引量:1
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  • 6Nemeth J A,Harb J F,Barroso U,et al.Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone[].Cancer Research.1999 被引量:1
  • 7Kerbel RS,Man MS,Dexter D.A model of human cancer metastasis: Extensive sponteneous and artificial metastasis of a human pigmented melanoma and derived variant sublines in nude mice[].Journal of the National Cancer Institute.1984 被引量:1
  • 8Asai T,Ueda T,Itoh K et al.Establishment and characterization of a murine osteosarcoma cell line ( LM8 ) with high metastatic potential to the lung[].International Journal of Cancer.1998 被引量:1

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