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阿莫西林致大疱性表皮坏死松解型药疹 被引量:4

Amoxycillin-induced epidermolysis bullosa
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摘要 A 56-year-old man experienced fever and pharyngitis and was self-treated with amoxycillin capsule 0.5g. 4 hours later, he developed redness and blisters on skin, more serious on head, neck, chest, back and arms. It was considered that the skin rash was associated with amoxycillin. The agent was withdrawn immediately and treated with dexamethasone, antibiotics and calamine lotion. His conditions were deteriorated progressively including a temperature of 39.7℃, skin redness and edema spreading to legs. The herpes were increased and fused while some were broken and dropped. The patient was diagnosed as epidermolysis bullosa. The symptoms lessened and resolved gradually after receiving dexamethasone, antibacterials and supportive treatment. A 56-year-old man experienced fever and pharyngitis and was self-treated with amoxycillin capsule 0.5g. 4 hours later, he developed redness and blisters on skin, more serious on head, neck, chest, back and arms. It was considered that the skin rash was associated with amoxycillin. The agent was withdrawn immediately and treated with dexamethasone, antibiotics and calamine lotion. His conditions were deteriorated progressively including a temperature of 39.7℃, skin redness and edema spreading to legs. The herpes were increased and fused while some were broken and dropped. The patient was diagnosed as epidermolysis bullosa. The symptoms lessened and resolved gradually after receiving dexamethasone, antibacterials and supportive treatment.
作者 吴军
出处 《药物不良反应杂志》 2005年第1期56-57,共2页 Adverse Drug Reactions Journal
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